Biomarker Analytical Core

Formerly the Hypertension Core Laboratory

 

Overview of Services 

 

The Biomarker Analytical Core (BAC) at Wake Forest School of Medicine is a CLIA-certified laboratory that performs clinical and research assays.  It serves as a reference laboratory for Wake Forest Baptist Medical Center, Winston-Salem, NC, as well as a central laboratory for Hypertension and Vascular Research.  The laboratory has participated in NIH, FDA, and pharmaceutical company-sponsored studies and has experience with multi-center projects.  K. Bridget Brosnihan, Ph.D. is certified as a high complexity assay laboratory director.  
The BAC provides analytical support for individual projects and for program project grants within the institution, as well as for national and international investigators.

The majority of the analytes are measured by radioimmunoassay (RIA), enzyme immunoassay (EIA), and enzymatic assays.  By having all the samples analyzed by staff with long-term experience, in a single laboratory equipped with appropriate instrumentation, data can be obtained in a more uniform manner, with the strictest possible quality control and minimal reagent expense.
The BAC is nationally and internationally recognized as an expert in measurement of components of the renin-angiotensin system, and provides biomarkers of cardiovascular, inflammatory, and aging-related and metabolic diseases.

Services:

  • Radioimmunoassay (RIA)
  • Enzyme Immunoassays (EIA)
  • Standard and Customized Multiplex ELISAS
  • High-Performance Liquid Chromatography (HPLC)
  • Mass spectrometry
  • Data analysis and consulting

Our Menu of Assays Include:

  • Hypertension Risk and Renal Injury Markers
  • Cytokines, Chemokines and Adhesion Molecules
  • Obesity and Metabolics Hormones
  • Stress, Aging and Inflammatory Markers
  • Vasoactive Peptides and Hormones
  • Sex Hormones

Leadership 

K. Bridget Brosnihan, PhD, HCLD
Director
Phone: (336) 716-2795
E-mail: bbrosnih@wakehealth.edu


TanYa Gwathmey-Williams, PhD
Co-Director

Phone: (336) 716-9524
E-mail: tgwathme@wakehealth.edu

 

Lab Contact 

Pam Dean
Lab Manager/Tech
Phone: (336)-716-3553
E-mail: pdean@wakehealth.edu

 

Location and Hours of Operation 

Hours Location

Monday - Friday

8:30 AM - 5:00 PM

Biomarker Analytical Core 
Biotech Place
575 N. Patterson Ave, 1S-Suite 134 
Winston, Salem, NC 27101
(336)-716-3553

Links and Resources

  1. Biomarker Analytical Core Website

Contacts

Name Role Phone Email Location
Pam Dean
Lab Manager/Tech
 
(336) 716-3553
 
pdean@wakehealth.edu
 
Biotech Place
 
TanYa Gwathmey
Co-Director
 
(336) 716-9524
 
tgwathme@wakehealth.edu
 
Biotech Place
 
K. Bridget Brosnihan
Professor, High Complexity Laboratory Director
 
(336) 716-2795
 
bbrosnih@wakehealth.edu
 
Biotech Place
 

Service list


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Assays (168)