Preclinical Ultrasound and Photoacoustic Imaging Core

Overview of Services

The Preclinical Ultrasound and Photoacoustic Imaging Core was established in July 2014 at Wake Forest School of Medicine as a research source for NIH-, foundation-, and industry-funded as well as early stage investigators at WFSM to study preclinical rodent models of human disease. It contains a new technology platform, Vevo F2 LAZR-X Photoacoustic imaging system, which offers high frequency ultrasound modalities of the extensively validated technology of the Vevo F2 and expands with a sophisticated laser and fiberoptic component enabling the inherent and real-time co-registration of photoacoustic and anatomical images in both 2D and 3D planes. This advanced imaging platform empowers investigators to obtain non-invasive and longitudinal anatomical, functional, physiological, and molecular data in relevant preclinical rodent models.


The instrument is housed on the 1st floor of BioTech Place Building in Hypertension and Vascular Research.


Areas of research that may benefit from Core services include but are not limited to:

  • diabetes
  • systemic and pulmonary hypertension
  • heart disease
  • peripheral artery disease
  • preeclampsia and intrauterine growth restriction
  • sepsis
  • aging
  • cancer


Nildris Cruz-Diaz, PhD
Director of the Preclinical Ultrasound and Photoacoustic Imaging Core (VEVO LAZR) 
Wake Forest School of Medicine
BioTech Place 575 N Patterson Avenue
Winston-Salem, NC 27101
Phone: 336-716-2340  

Location and hours of operation

Hours Location

Monday - Friday

8 AM - 5 PM

Hypertension & Vascular Research 
Wake Forest School of Medicine
 BioTech Place 575 N. Patterson Avenue, Suite 120
Winston-Salem, NC 27101

Links and Resources

  1. Preclinical Microultrasound and Photoacoustic Imaging Core Website


Name Role Phone Email Location
Nildris Cruz-Diaz, PhD
Core Co-Director
Biotech Place Suite 120
Liliya M. Yamaleyeva, MD, MS
Core Co-Director
Biotech Place Suite 340

Service list

Search available services: View: by category alphabetically
Photoacoustic Imaging (4)
Ultrasound Imaging (11)